Description
Prostate specific antigen (PSA) is produced by prostate glandular and endothelial cells.It is a single chain glycoprotein with a molecular weight of approximately 34 kDa. PSA exists in three major forms circulating in the serum. These forms are free PSA, PSA bound to α1 – Antichymotrypsin (PSA-ACT) and PSA complexed with α2– macroglobulin (PSA-MG).